Do Children With Fragile X Syndrome Show Declines or Plateaus in Adaptive Behavior?

Laura J. Hahn, Nancy C. Brady, Steven F. Warren, Kandace K. Fleming

Research output: Contribution to journalArticlepeer-review


This study explores if children with fragile X syndrome (FXS) show advances, declines, or plateaus in adaptive behavior over time and the relationship of nonverbal cognitive abilities and autistic behavior on these trajectories. Parents of 55 children with FXS completed the Vineland Adaptive Behavior Scales ( Sparrow, Balla, & Cicchetti, 1984 ; Sparrow, Cicchetti, & Balla, 2005 ) between 3 and 6 times from 2 to 10 years of age. Using raw scores, results indicate that about half of the sample showed advances in adaptive behavior, whereas the other half showed declines, indicating a regression in skills. Children who were more cognitively advanced and had less autistic behaviors had higher trajectories. Understanding the developmental course of adaptive behavior in FXS has implications for educational planning and intervention, especially for those children showing declines.

Original languageEnglish (US)
Pages (from-to)412-432
Number of pages21
JournalAmerican journal on intellectual and developmental disabilities
Issue number5
StatePublished - Sep 1 2015


  • adaptive behavior
  • developmental trajectory
  • fragile X syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health


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