DNA-mediated artificial nanobiostructures: State of the art and future directions

Research output: Contribution to journalArticlepeer-review

Abstract

DNA (deoxyribonucleic acid)-mediated assembly of nanometer and micrometer scale structures can have a profound impact in the fields of nanoelectronics and nanotechnology. Such structures can also find applications in microelectromechanical systems, hybrid bio-sensors, and the potential to continue the scaling of Moore's law beyond the 50 nm node. While engineers and scientists have been long aspiring to controllably and specifically manipulate structures at the micrometer and nanometer scale, nature has been performing these tasks and assembling structures with great accuracy and high efficiency using highly specific biological molecules such as DNA and proteins. This paper describes the motivations and fundamentals behind these assembly concepts, with a focus on DNA hybridization-mediated assembly, and presents the state of the art in this field. In addition, new ideas and directions for future research on DNA-mediated assembly of active devices and DNA-based molecular devices are also presented.

Original languageEnglish (US)
Pages (from-to)1-16
Number of pages16
JournalSuperlattices and Microstructures
Volume29
Issue number1
DOIs
StatePublished - Jan 2001
Externally publishedYes

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Electrical and Electronic Engineering

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