DNA-cationic amphiphile interactions

Maria G. Miguel; Alberto A.C.C. Pais; Rita S. Dias; Cecília Leal; Mónica Rosa; Björn Lindman

doi:10.1016/S0927-7757(03)00334-0

DNA-cationic amphiphile interactions

Maria G. Miguel
, Alberto A.C.C. Pais
, Rita S. Dias
, Cecília Leal
, Mónica Rosa
, Björn Lindman

Research output: Contribution to journal › Article › peer-review

Abstract

DNA shows strong interactions with cationic cosolutes and these have both biological and technological significance. We outline our research on various mixed systems of DNA and cationic amphiphiles including the interaction of DNA with simple cationic surfactants as well as the interaction with catanionic mixtures and positively charged catanionic vesicles. An overview from phase behavior to microstructure will be presented. We will also address DNA compaction and decompaction phenomena in different systems. Finally, simulations on DNA confinement and interaction with cationic polyions are considered.

Original language	English (US)
Pages (from-to)	43-55
Number of pages	13
Journal	Colloids and Surfaces A: Physicochemical and Engineering Aspects
Volume	228
Issue number	1-3
DOIs	https://doi.org/10.1016/S0927-7757(03)00334-0
State	Published - Nov 1 2003
Externally published	Yes

Keywords

Amino acid-based surfactants
Catanionic mixtures
Catanionic vesicles
Cationic amphiphiles/surfactants
Cryo-TEM
DNA
DNA compaction/decompaction
DNA hydration
DNA-amphiphile complexes
Fluorescence microscopy
Phase behavior
Polyions

ASJC Scopus subject areas

Colloid and Surface Chemistry
Physical and Theoretical Chemistry

Online availability

10.1016/S0927-7757(03)00334-0

Library availability

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Cite this

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title = "DNA-cationic amphiphile interactions",

abstract = "DNA shows strong interactions with cationic cosolutes and these have both biological and technological significance. We outline our research on various mixed systems of DNA and cationic amphiphiles including the interaction of DNA with simple cationic surfactants as well as the interaction with catanionic mixtures and positively charged catanionic vesicles. An overview from phase behavior to microstructure will be presented. We will also address DNA compaction and decompaction phenomena in different systems. Finally, simulations on DNA confinement and interaction with cationic polyions are considered.",

keywords = "Amino acid-based surfactants, Catanionic mixtures, Catanionic vesicles, Cationic amphiphiles/surfactants, Cryo-TEM, DNA, DNA compaction/decompaction, DNA hydration, DNA-amphiphile complexes, Fluorescence microscopy, Phase behavior, Polyions",

author = "Miguel, \{Maria G.\} and Pais, \{Alberto A.C.C.\} and Dias, \{Rita S.\} and Cec{\'i}lia Leal and M{\'o}nica Rosa and Bj{\"o}rn Lindman",

note = "The work described here was supported by grants from JNICT and Praxis XXI (PRAXIS/BD/21227/99), the Funda{\c c}{\~a}o para a Ci{\^e}ncia e Tecnologia (FCT) (Project Sapiens PCTI/99/QUI/35414), Portugal, the Swedish Research Council for Engineering Sciences (TFR), and the Center for Amphiphilic Polymers (CAP), in Lund, Sweden. We acknowledge greatly the support from extensive knowledge of simple and complex systems and self-assembly, as well and experimental facilities, of Physical Chemistry 1 in Lund. The work reported on DNA hydration is done under the direction of Gerd Olofsson, Lars Wads{\"o} and H{\aa}kan Wennerstr{\"o}m. The simulation work is much stimulated by collaboration and support from Per Linse. The work on amino acid-based surfactant is made in collaboration with Maria Rosa Infante, Barcelona. We also acknowledge discussions in our network, including groups in Munich (Joachim R{\"a}dler), Dublin (Kenneth Dawson) and Paris (Dominique Langevin).",

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doi = "10.1016/S0927-7757(03)00334-0",

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AU - Pais, Alberto A.C.C.

AU - Dias, Rita S.

AU - Leal, Cecília

AU - Rosa, Mónica

AU - Lindman, Björn

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PY - 2003/11/1

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N2 - DNA shows strong interactions with cationic cosolutes and these have both biological and technological significance. We outline our research on various mixed systems of DNA and cationic amphiphiles including the interaction of DNA with simple cationic surfactants as well as the interaction with catanionic mixtures and positively charged catanionic vesicles. An overview from phase behavior to microstructure will be presented. We will also address DNA compaction and decompaction phenomena in different systems. Finally, simulations on DNA confinement and interaction with cationic polyions are considered.

AB - DNA shows strong interactions with cationic cosolutes and these have both biological and technological significance. We outline our research on various mixed systems of DNA and cationic amphiphiles including the interaction of DNA with simple cationic surfactants as well as the interaction with catanionic mixtures and positively charged catanionic vesicles. An overview from phase behavior to microstructure will be presented. We will also address DNA compaction and decompaction phenomena in different systems. Finally, simulations on DNA confinement and interaction with cationic polyions are considered.

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KW - DNA

KW - DNA compaction/decompaction

KW - DNA hydration

KW - DNA-amphiphile complexes

KW - Fluorescence microscopy

KW - Phase behavior

KW - Polyions

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DNA-cationic amphiphile interactions

Abstract

Keywords

ASJC Scopus subject areas

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