DNA-catalyzed glycosylation using aryl glycoside donors

Anthony R. Hesser, Benjamin M. Brandsen, Shannon M. Walsh, Puzhou Wang, Scott K Silverman

Research output: Contribution to journalArticle

Abstract

We report the identification by in vitro selection of Zn2+/Mn2+-dependent deoxyribozymes that glycosylate the 3′-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

Original languageEnglish (US)
Pages (from-to)9259-9262
Number of pages4
JournalChemical Communications
Volume52
Issue number59
DOIs
StatePublished - Jan 1 2016

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Catalytic DNA
Glycosylation
Glycosides
DNA
Oligonucleotides

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

DNA-catalyzed glycosylation using aryl glycoside donors. / Hesser, Anthony R.; Brandsen, Benjamin M.; Walsh, Shannon M.; Wang, Puzhou; Silverman, Scott K.

In: Chemical Communications, Vol. 52, No. 59, 01.01.2016, p. 9259-9262.

Research output: Contribution to journalArticle

Hesser, AR, Brandsen, BM, Walsh, SM, Wang, P & Silverman, SK 2016, 'DNA-catalyzed glycosylation using aryl glycoside donors', Chemical Communications, vol. 52, no. 59, pp. 9259-9262. https://doi.org/10.1039/c6cc04329a
Hesser, Anthony R. ; Brandsen, Benjamin M. ; Walsh, Shannon M. ; Wang, Puzhou ; Silverman, Scott K. / DNA-catalyzed glycosylation using aryl glycoside donors. In: Chemical Communications. 2016 ; Vol. 52, No. 59. pp. 9259-9262.
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