DNA-catalyzed glycosylation using aryl glycoside donors

Anthony R. Hesser, Benjamin M. Brandsen, Shannon M. Walsh, Puzhou Wang, Scott K. Silverman

Research output: Contribution to journalArticle

Abstract

We report the identification by in vitro selection of Zn2+/Mn2+-dependent deoxyribozymes that glycosylate the 3′-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.

Original languageEnglish (US)
Pages (from-to)9259-9262
Number of pages4
JournalChemical Communications
Volume52
Issue number59
DOIs
StatePublished - 2016

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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