Divalent 2-(4-Hydroxyphenyl)benzothiazole Bifunctional Chelators for ⁶⁴Cu Positron Emission Tomography Imaging in Alzheimer's Disease

Keyphrases

• Bifunctional Chelator 100%
• P-hydroxyphenyl 100%
• Alzheimer's Disease 100%
• Positron Emission Tomography 100%
• Divalent 100%
• Benzothiazole 100%
• High Affinity 33%
• Cu(II) 33%
• Partition Coefficient 33%
• Binding Affinity 33%
• Wild Mice 33%
• New Series 33%
• Form-stable 33%
• Lipophilicity 33%
• Biodistribution Studies 33%
• Amyloid Aggregates 33%
• Brain Uptake 33%
• Amyloid Plaques 33%
• In Vitro Autoradiography 33%
• Carboxylate Ester 33%
• Pendant Arm 33%
• Alkyl Carboxylates 33%
• Blood-brain Barrier Penetration 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Chelating Agent 100%
• Copper 64 100%
• Alzheimer's Disease 100%
• Divalent 100%
• Benzothiazole 100%
• Cuprous Ion 25%
• Carboxylate 25%
• Biodistribution 25%
• Autoradiography 25%
• Wild Type Mouse 25%
• Lipophilicity 25%
• Amyloid Protein 25%
• Amyloid Plaque 25%
• Blood-Brain Barrier 25%

Material Science

• Tomography 100%