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Distinct amino acid-sensing mTOR pathways regulate skeletal myogenesis
Mee Sup Yoon,
Jie Chen
Cell and Developmental Biology
Carl R. Woese Institute for Genomic Biology
Biomedical and Translational Sciences
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peer-review
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Dive into the research topics of 'Distinct amino acid-sensing mTOR pathways regulate skeletal myogenesis'. Together they form a unique fingerprint.
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Keyphrases
Amino Acid Activation
16%
Amino Acid Availability
16%
Amino Acid Sensing
100%
Amino Acids
50%
Availability Management
16%
C2C12 Myoblasts
16%
Cell Growth Regulation
16%
Cellular Processes
16%
Class III Phosphoinositide 3-kinase
16%
Context Dependence
16%
Developmental Processes
16%
Homeostasis
16%
Inducer
16%
Inhibitory Activity
16%
Insulin Receptor Substrate 1 (IRS1)
16%
Insulin-like Growth Factor 2 (IGF2)
33%
Kinase-independent
16%
Knockdown
16%
Mammalian Target of Rapamycin (mTOR)
100%
Mammalian Target of Rapamycin Pathway
100%
Mammalian Target of Rapamycin Signaling
16%
Master Regulator
16%
Myogenesis
33%
Myogenic Differentiation
50%
Overexpression
16%
Phosphatidic Acid
16%
Phosphoinositide 3-kinase (PI3K)
16%
Phospholipase D1 (PLD1)
16%
Rag GTPases
16%
Raga
16%
Rapamycin
16%
Sensing Mechanism
16%
Skeletal Myogenesis
100%
Target of Rapamycin Kinase
16%
Vps34
66%
Biochemistry, Genetics and Molecular Biology
Amino Acids
100%
C2C12
16%
Cell Growth
16%
Enhancer Region
33%
Growth Regulation
16%
Homeostasis
16%
Insulin-Like Growth Factor 2
16%
IRS1
16%
Mammalian Target of Rapamycin
33%
Mammalian Target of Rapamycin Complex 1
16%
Mechanistic Target of Rapamycin
100%
Mediator
16%
Myogenesis
100%
Phosphatidic Acid
16%
Phosphoinositide 3-Kinase
33%
Phospholipase D1
16%
RNA Translation
16%