@inproceedings{bb89790d549c420da4eb66ed769b27a5,
title = "Dissolvable hydrogels as transducers of bio-chemical signals: Models and simulations",
abstract = "Hydrogels have a large number of applications in microelectromechanical systems (MEMS) technology as sensors and actuators. In this paper we investigate the use of responsive micro-sized hydrogels as transducers of biochemical signals. Hydrogels, crosslinked via disulfide bonds, when immersed in a solution containing a disulfide reducing agent can dissolve as the covalent cross-links are cleaved by the reducing agent and thereby indicate the presence of the cleaving agent. As a result, this phenomenon leads to the transduction of chemical signal to visual signal. The mechanism of the hydrogel dissolution process has been studied in detail and a mathematical model has been developed. From the vanishing time of the dissolvable hydrogel, a significant amount of information about the surrounding bath solution can be obtained.",
keywords = "Actuators, Biological system modeling, Chemical sensors, Chemical technology, Chemical transducers, Mathematical model, Microelectromechanical systems, Micromechanical devices, Polymers, Sensor systems and applications",
author = "Chatterjee, {A. N.} and Moore, {J. S.} and Beebe, {D. J.} and Aluru, {N. R.}",
note = "Publisher Copyright: {\textcopyright} 2003 IEEE.; 12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers ; Conference date: 08-06-2003 Through 12-06-2003",
year = "2003",
doi = "10.1109/SENSOR.2003.1215578",
language = "English (US)",
series = "TRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "734--737",
booktitle = "TRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers",
address = "United States",
}