Turns and bends, such as an L-turn or a U-turn, in micro and nano-fluidic channels can induce significant dispersion leading to a low efficiency electrophoretic separation process. It has been shown that turn-induced dispersion can be lowered by optimizing the geometry of the turns. In this paper, we propose a new approach for controlling turn-induced dispersion in nano-fluidic channels. The approach is based on the idea of locally controlling the ζ-potential at turns and bends. An optimization algorithm was developed to search for the optimal configuration of the ζ-potential near turns. Results for an L-turn and a U-turn show that the dispersion can be lowered significantly by a localized ζ-potential variation near the turn.
- Dispersion control
- Nano-fluidic channels
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Mechanical Engineering