Disentangling the mechanistic role of loop-C capping in Cys-loop receptor activation

Keyphrases

• Mechanistic Role 100%
• Receptor Activation 100%
• Cys-loop Receptor 100%
• Neurotransmitters 66%
• Binding Site 66%
• Agonist Binding 66%
• Atomic Model 33%
• Low Affinity 33%
• Extracellular Domain 33%
• High Affinity 33%
• Membrane Pore 33%
• Bound States 33%
• Mutagenesis 33%
• Functional Impact 33%
• Mechanical Link 33%
• Local Change 33%
• Functional Assay 33%
• Chimeric Construct 33%
• Large Rearrangements 33%

Biochemistry, Genetics and Molecular Biology

• Capping Phenomenon 100%
• Cys-Loop Receptors 100%
• Agonist 75%
• Neurotransmitter 50%
• Binding Site 50%
• Mutagenesis 25%
• Conformation 25%