Discovery of the DNA "genetic code" for abiological gold nanoparticle morphologies

Zidong Wang, Longhua Tang, Li Huey Tan, Jinghong Li, Yi Lu

Research output: Contribution to journalArticlepeer-review


DNA is in control: Different combinations of DNA nucleotides can control the shape and surface roughness of gold nanoparticles during their synthesis. These nanoparticles were synthesized in the presence of either homogenous oligonucleotides or mixed-base oligonucleotides using gold nanoprisms as seeds. The effect of the individual DNA bases and their combinations on shape control are shown in the figure.

Original languageEnglish (US)
Pages (from-to)9078-9082
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number36
StatePublished - Sep 3 2012


  • DNA
  • genetic code
  • gold
  • nanoparticle synthesis
  • nanoparticles

ASJC Scopus subject areas

  • General Chemistry
  • Catalysis


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