Directed evolution of soluble single-chain human class II MHC molecules

Keyphrases

• Directed Evolution 100%
• Yeast Cells 100%
• Major Histocompatibility Complex Molecules 100%
• Cell Surface 100%
• Protein Folding 66%
• Peptide Binding 66%
• High Sensitivity 33%
• Amino Acid Residues 33%
• Recombinant 33%
• Major Histocompatibility Complex 33%
• Binding Properties 33%
• Binding Affinity 33%
• Therapeutic Use 33%
• Random mutagenesis 33%
• Yeast Surface Display 33%
• Site-directed mutant 33%
• MHC Class II 33%
• T Cells 33%
• Flow Cytometry 33%
• Hydrophobic Core 33%
• Expression Characterization 33%
• Functional Characterization 33%
• Technology Platform 33%
• Molecular Modeling Studies 33%
• Diagnostic Applications 33%
• Binding Specificity 33%
• Functional Expression 33%
• Soluble Form 33%
• Human Leukocyte Antigen 33%
• Rapid Kinetics 33%
• Antigenic Peptide 33%
• Immunofluorescence Labeling 33%
• Fluorescence-activated Cell Sorting 33%
• Multiple Disulfide Bonds 33%
• Expression Stability 33%
• Expression Engineering 33%
• Specific Peptide 33%
• Flow Cytometric Assay 33%
• Folding Efficiency 33%

Biochemistry, Genetics and Molecular Biology

• Major Histocompatibility Complex 100%
• Surface Property 80%
• Protein Folding 40%
• Amino Acids 20%
• Mutagenesis 20%
• Disulfide Bond 20%
• T Cell 20%
• Conformation 20%
• Immunofluorescence 20%
• Copurification 20%
• Molecular Model 20%
• Molecular Modeling 20%
• Lymphocyte 20%
• Flow Cytometry 20%
• Monospecific Antibody 20%
• Fluorescence Activated Cell Sorting 20%

Immunology and Microbiology

• Major Histocompatibility Complex 100%
• Cell Surface 60%
• Yeast Cell 60%
• Protein Folding 40%
• Monospecific Antibody 20%
• T Cell 20%
• Disulfide Bond 20%
• Surface Property 20%
• Immunofluorescence 20%
• Mutagenesis 20%
• Conformation 20%
• Fluorescence Labeling 20%
• Fluorescence Activated Cell Sorting 20%
• Lymphocyte Antigen 20%
• Molecular Model 20%