Directed evolution of enzymes and pathways for industrial biocatalysis

Huimin Zhao, Karuppiah Chockalingam, Zhilei Chen

Research output: Contribution to journalReview articlepeer-review


Directed evolution has become a powerful tool for developing enzyme and whole cell based biocatalysts. Significant recent advances include the creation of novel enzyme functions and the development of several new efficient directed evolution methods. The combination of directed evolution and rational design promises to accelerate the development of biocatalysts for applications in the pharmaceutical, chemical and food industries.

Original languageEnglish (US)
Pages (from-to)104-110
Number of pages7
JournalCurrent Opinion in Biotechnology
Issue number2
StatePublished - Apr 1 2002

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering


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