TY - JOUR
T1 - Directed evolution of enzymes and pathways for industrial biocatalysis
AU - Zhao, Huimin
AU - Chockalingam, Karuppiah
AU - Chen, Zhilei
PY - 2002/4/1
Y1 - 2002/4/1
N2 - Directed evolution has become a powerful tool for developing enzyme and whole cell based biocatalysts. Significant recent advances include the creation of novel enzyme functions and the development of several new efficient directed evolution methods. The combination of directed evolution and rational design promises to accelerate the development of biocatalysts for applications in the pharmaceutical, chemical and food industries.
AB - Directed evolution has become a powerful tool for developing enzyme and whole cell based biocatalysts. Significant recent advances include the creation of novel enzyme functions and the development of several new efficient directed evolution methods. The combination of directed evolution and rational design promises to accelerate the development of biocatalysts for applications in the pharmaceutical, chemical and food industries.
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U2 - 10.1016/S0958-1669(02)00291-4
DO - 10.1016/S0958-1669(02)00291-4
M3 - Review article
C2 - 11950559
AN - SCOPUS:0036536478
SN - 0958-1669
VL - 13
SP - 104
EP - 110
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
IS - 2
ER -