Abstract
An angiogenic microfiber patch that releases angiogenic growth factors along aligned fibers and subsequently directs the spacing and orientation of mature and functional blood vessel formation is presented. The fiber patches are prepared by electrostatically binding electrosprayed vascular endothelial growth factor (VEGF)-encapsulating poly(lactide-co-glycolide) (PLGA) microparticles with electrospun poly(lactide) (PLA) microfibers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3139-3143 |
| Number of pages | 5 |
| Journal | Advanced Materials |
| Volume | 23 |
| Issue number | 28 |
| DOIs | |
| State | Published - Jul 26 2011 |
Keywords
- drug delivery
- fibers
- microstructures
- polymeric materials
- tissue engineering
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering