Dihydrofolate Reductase: Hydrogen Tunneling and Protein Motion

Stephen J. Benkovic, Sharon Hammes-Schiffer

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationHydrogen-Transfer Reactions
PublisherJohn Wiley & Sons, Ltd.
Pages1439-1454
Number of pages16
Volume4
ISBN (Print)9783527307777
DOIs
StatePublished - Jul 17 2007
Externally publishedYes

Keywords

  • Action of specific enzyme systems
  • Biological aspects
  • Dihydrofolate reductase (DHFR)
  • Enzyme motion in DHFR catalysis
  • Hydrogen transfer
  • Hydrogen tunneling
  • Protein motion
  • Reaction catalysis
  • Reaction chemistry
  • Structural features of DHFR

ASJC Scopus subject areas

  • General Chemistry

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