Abstract
Young adult male BALB/c mice were intraperitoneally injected with 400 mg butylated hydroxytoluene/kg body weight and immediately placed in 70% oxygen for 6 days. An extensive interstitial pulmonary fibrosis developed 14 days after the beginning of the experiment. An increase in lung collagen was confirmed electron-microscopically. Comparison with human disease and usefulness of this animal model are discussed. (Nizze - Rostock)
Original language | English (US) |
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Pages (from-to) | 333-335 |
Number of pages | 3 |
Journal | American Journal of Pathology |
Volume | 105 |
Issue number | 3 |
State | Published - 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Pathology and Forensic Medicine