Differential responses of N-nitrosoamines and aromatic amines in the plant cell/microbe coincubation assay

T. Gichner, E. D. Wagner, Michael Jacob Plewa

Research output: Contribution to journalArticle

Abstract

The plant cell/microbe coincubation assay is based on employing living tobacco cells in suspension culture as the activating system for promutagens and the Ames/Salmonella cells as the genetic indicator system. In contrast to aromatic amines (e.g. 2-aminofluorene and m-phenylenediamine) that were previously reported to be activated to products mutagenic in the S. typhimurium strains TA98 or YG1024 by tobacco cells, promutagenic N-nitrosoamines (N-nitrosodimethylamine, N-nitroso-morpholine, N-nitrosopiperidine, N-nitrosomethyl-2-hydroxypropylamine) were not activated to product(s) mutagenic in S. typhimurium TA 100.

Original languageEnglish (US)
Pages (from-to)401-406
Number of pages6
JournalBiologia Plantarum
Volume35
Issue number3
DOIs
StatePublished - Sep 1 1993

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aromatic amines
microorganisms
assays
tobacco
cells
cell suspension culture
Salmonella

ASJC Scopus subject areas

  • Plant Science
  • Horticulture

Cite this

Differential responses of N-nitrosoamines and aromatic amines in the plant cell/microbe coincubation assay. / Gichner, T.; Wagner, E. D.; Plewa, Michael Jacob.

In: Biologia Plantarum, Vol. 35, No. 3, 01.09.1993, p. 401-406.

Research output: Contribution to journalArticle

Gichner, T. ; Wagner, E. D. ; Plewa, Michael Jacob. / Differential responses of N-nitrosoamines and aromatic amines in the plant cell/microbe coincubation assay. In: Biologia Plantarum. 1993 ; Vol. 35, No. 3. pp. 401-406.
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