Differential responses of N-nitrosoamines and aromatic amines in the plant cell/microbe coincubation assay

T. Gichner, E. D. Wagner, Michael Jacob Plewa

Research output: Contribution to journalArticle

Abstract

The plant cell/microbe coincubation assay is based on employing living tobacco cells in suspension culture as the activating system for promutagens and the Ames/Salmonella cells as the genetic indicator system. In contrast to aromatic amines (e.g. 2-aminofluorene and m-phenylenediamine) that were previously reported to be activated to products mutagenic in the S. typhimurium strains TA98 or YG1024 by tobacco cells, promutagenic N-nitrosoamines (N-nitrosodimethylamine, N-nitroso-morpholine, N-nitrosopiperidine, N-nitrosomethyl-2-hydroxypropylamine) were not activated to product(s) mutagenic in S. typhimurium TA 100.

Original languageEnglish (US)
Pages (from-to)401-406
Number of pages6
JournalBiologia Plantarum
Volume35
Issue number3
DOIs
StatePublished - Sep 1 1993

ASJC Scopus subject areas

  • Plant Science
  • Horticulture

Fingerprint Dive into the research topics of 'Differential responses of N-nitrosoamines and aromatic amines in the plant cell/microbe coincubation assay'. Together they form a unique fingerprint.

  • Cite this