Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry

Keyphrases

• Hydrogen Bonds (H-bonds) 100%
• Hydroxylation 100%
• Lyase 100%
• CYP17 100%
• Nanodiscs 50%
• Raman Spectra 50%
• Hydrogen Bonding Interaction 50%
• Substrate Structure 50%
• Progesterone 50%
• Reaction Pathway 50%
• Natural Substrate 50%
• Physiological Implications 50%
• Pregnenolone 50%
• Substrate Control 50%

Chemistry

• Chemistry 100%
• Hydrogen Bonding 100%
• hydroxylation 100%
• Nanodisc 50%
• Progesterone 50%
• Pregnenolone 50%
• Raman Spectra 50%

Biochemistry, Genetics and Molecular Biology

• Hydroxylation 100%
• Lyase 100%
• Progesterone 100%
• Pregnenolone 100%