Different distributions of calbindin and calretinin immunostaining across the medial and dorsal divisions of the mouse medial geniculate body

E. Lu, D. A. Llano, S. M. Sherman

Research output: Contribution to journalArticlepeer-review

Abstract

We studied the distributions of calretinin and calbindin immunoreactivity in subdivisions of the mouse medial geniculate body and the adjacent paralaminar nuclei. We found that the vast majority of labeled cells in the dorsal division of the medial geniculate body were immunoreactive for calbindin-only, whereas most of the remaining labeled cells were double-labeled. Very few calretinin+ only cells were observed. By contrast, we observed significant proportions of calbindin+ only, calretinin+ only and double-labeled cells in the medial division of the medial geniculate body. Further, the distributions of calbindin-only, calretinin-only and double-labeled cells did not differ between the medial division of the medial geniculate body, the suprageniculate nucleus, the peripeduncular nucleus and the posterior intralaminar nucleus. We found essentially no somatic staining for either calbindin or calretinin in the ventral division of the medial geniculate body. These data suggest that there are distinct neurochemical differences between the two non-lemniscal auditory thalamic nuclei. In addition, these data extend previous observations that the medial division of the medial geniculate body shares many properties with the paralaminar group of nuclei.

Original languageEnglish (US)
Pages (from-to)16-23
Number of pages8
JournalHearing Research
Volume257
Issue number1-2
DOIs
StatePublished - Nov 2009

Keywords

  • Auditory
  • Calcium
  • Cortex
  • Intralaminar
  • Paralaminar
  • Thalamus

ASJC Scopus subject areas

  • Sensory Systems

Fingerprint Dive into the research topics of 'Different distributions of calbindin and calretinin immunostaining across the medial and dorsal divisions of the mouse medial geniculate body'. Together they form a unique fingerprint.

Cite this