Diet and cancer prevention: Current knowledge and future direction

Elizabeth H. Jeffery, John A. Milner

Research output: Chapter in Book/Report/Conference proceedingChapter


It is now more than two decades since Doll and Peto suggested that dietary choices might modulate cancer risk (Doll and Peto, 1981). Whereas their assumption was based chiefly on epidemiological findings, evidence from a variety of sources during the past 20 years has largely substantiated the idea that diet can significantly influence cancer incidence and tumor behavior. Detailed mechanistic studies have identified multiple effects for a number of individual food components on various cancerrelated processes (Figure 17.1). However, the absolute response to these bioactive food components is likely dependent on multiple factors, including a host of dietary and environmental interactions as well the genetic profile of the consumer. Thus, it is logical to expect considerable variation, as is evident in the published literature.

Original languageEnglish (US)
Title of host publicationCarcinogenic and Anticarcinogenic Food Components
PublisherCRC Press
Number of pages34
ISBN (Electronic)9781420039269
ISBN (Print)0849320968, 9780849320965
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • General Engineering
  • General Agricultural and Biological Sciences


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