Diagnostic Enzymology of Domestic Animals

Walter E. Hoffmann, Philip F. Solter

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter presents an overview of the diagnostic enzymology of domestic animals. Clinical enzymology is the discipline that studies and tests enzyme activity in serum, plasma, urine, or other body fluids to help establish the diagnosis and prognosis of disease, and to screen for abnormal organ function. The automation of enzyme assays, and the popularity of the serum chemistry profile in veterinary medicine, has allowed retrospective studies to be conducted and has given veterinarians an opportunity to critically evaluate the diagnostic function of the common assays in a large number of animals on a regular basis, as well as gain a "feel" for the results, thereby allowing for more subtle clinical interpretations. This chapter explores the universal factors affecting changes in enzyme content of bodily fluids. The chapter then delves into specific details relevant to particular enzymes. Discussion of basic concepts in enzymology, such as enzyme structure, kinetics, or analysis, is limited to those that are of clinical relevance or that add insight into interpreting changes in body fluid enzyme activity.

Original languageEnglish (US)
Title of host publicationClinical Biochemistry of Domestic Animals, Sixth Edition
Number of pages28
ISBN (Electronic)9780123704917
StatePublished - Jan 1 2008

ASJC Scopus subject areas

  • General Engineering
  • General Agricultural and Biological Sciences


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