This chapter presents an overview of the diagnostic enzymology of domestic animals. Clinical enzymology is the discipline that studies and tests enzyme activity in serum, plasma, urine, or other body fluids to help establish the diagnosis and prognosis of disease, and to screen for abnormal organ function. The automation of enzyme assays, and the popularity of the serum chemistry profile in veterinary medicine, has allowed retrospective studies to be conducted and has given veterinarians an opportunity to critically evaluate the diagnostic function of the common assays in a large number of animals on a regular basis, as well as gain a "feel" for the results, thereby allowing for more subtle clinical interpretations. This chapter explores the universal factors affecting changes in enzyme content of bodily fluids. The chapter then delves into specific details relevant to particular enzymes. Discussion of basic concepts in enzymology, such as enzyme structure, kinetics, or analysis, is limited to those that are of clinical relevance or that add insight into interpreting changes in body fluid enzyme activity.
|Original language||English (US)|
|Title of host publication||Clinical Biochemistry of Domestic Animals, Sixth Edition|
|Number of pages||28|
|State||Published - Jan 1 2008|
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)