Diagnosis of Human-Pathogenic Staphylococcus in Surveillance and Outbreak Detection

Nabanita Mukherjee, Goutam Banerjee, Saumya Agarwal, Pratik Banerjee

Research output: Chapter in Book/Report/Conference proceedingChapter


Staphylococcus is known to cause a wide range of illnesses in humans. Staphylococcus aureus, one of the most commonly reported human pathogenic Staphylococcus species, causes bacteremia, endocarditis, skin and soft tissue infections, and infections associated with medical devices. A serious global public health concern is the increasing prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) infections in healthcare and community settings. MRSA can infect both humans and animals. Infection caused by MRSA is often challenging to treat because of its resistance to multiple drugs. This chapter covers the sources, epidemiology, pathophysiology, molecular detection approaches in surveillance, and outbreaks of human pathogenic Staphylococcal infections in detail. The sources of human pathogenic Staphylococcus and the mechanism of bacterial transmission via animal origin, environment, food handlers, and companion animals are also discussed. In-depth descriptions of Staphylococcal virulence factors, enterotoxins, antibiotic resistance, and biofilm formation are also included. In addition, various methods of molecular identification of Staphylococcus, including PCR, Mass Spectrometry, VITEK 2, and Whole Genome Sequencing, were presented in the chapter.

Original languageEnglish (US)
Title of host publicationDiagnosis of Pathogenic Microorganisms Causing Infectious Diseases
PublisherCRC Press
Number of pages43
ISBN (Electronic)9780429672750
ISBN (Print)9780367029265
StatePublished - Jan 1 2024

ASJC Scopus subject areas

  • General Medicine
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Engineering


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