TY - JOUR
T1 - Development of Photoacoustic Probes for in Vivo Molecular Imaging
AU - Reinhardt, Christopher J.
AU - Chan, Jefferson
N1 - *Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801. E-mail: [email protected]. Telephone: (217) 300-2767. ORCID Christopher J. Reinhardt: 0000-0001-9992-1253 Jefferson Chan: 0000-0003-4139-4379 Funding C.J.R. was supported by Chemistry-Biology Interface Training Grant 2T32 GM070421. Additional financial support came from the Alfred P. Sloan fellowship (FG-2017-8964 to J.C.). Notes The authors declare no competing financial interest.
PY - 2018/1/16
Y1 - 2018/1/16
N2 - Photoacoustic (PA) imaging is an emerging, non-invasive imaging modality that encompasses attributes of both optical and ultrasound imaging. Because of the combination of optical excitation and acoustic detection, PA imaging enables high contrast and high resolution within deep tissue (centimeter depths). Recent advances in PA probe development have allowed for stimulus-responsive imaging in a variety of biological models with implications for basic, translational, and clinical sciences. This perspective highlights recent progress in the development of PA probes and their application to live-animal molecular imaging.
AB - Photoacoustic (PA) imaging is an emerging, non-invasive imaging modality that encompasses attributes of both optical and ultrasound imaging. Because of the combination of optical excitation and acoustic detection, PA imaging enables high contrast and high resolution within deep tissue (centimeter depths). Recent advances in PA probe development have allowed for stimulus-responsive imaging in a variety of biological models with implications for basic, translational, and clinical sciences. This perspective highlights recent progress in the development of PA probes and their application to live-animal molecular imaging.
UR - https://www.scopus.com/pages/publications/85040620314
UR - https://www.scopus.com/pages/publications/85040620314#tab=citedBy
U2 - 10.1021/acs.biochem.7b00888
DO - 10.1021/acs.biochem.7b00888
M3 - Review article
C2 - 29022344
AN - SCOPUS:85040620314
SN - 0006-2960
VL - 57
SP - 194
EP - 199
JO - Biochemistry
JF - Biochemistry
IS - 2
ER -