Development of inflammatory bowel disease is linked to a longitudinal restructuring of the gut metagenome in mice

Keyphrases

• Inflammatory Bowel Disease 100%
• Gut Metagenome 100%
• Gut Microbiome 50%
• Disease Development 33%
• Immune Activation 25%
• Mouse Model 16%
• Metagenomics 16%
• Microbiome 16%
• Disease Mechanisms 16%
• Gut Microbial Community 16%
• Microbial Pathways 16%
• Early Biomarker 16%
• Mechanistic Insight 8%
• Host-microbe Interactions 8%
• Microbial Community 8%
• Human Disease 8%
• T Cell Activation 8%
• Transforming Growth Factor-β 8%
• Microbes 8%
• T Cells 8%
• Functional Capacity 8%
• Generalized Linear Mixed Model 8%
• Weight Loss 8%
• Longitudinal Design 8%
• Chemotaxis 8%
• Functional Diversity 8%
• Disease Severity 8%
• Functional Pathways 8%
• Host Immune Response 8%
• Sick 8%
• Peripheral Blood 8%
• Secretion Systems 8%
• Growth Factor Signaling 8%
• Temporal Dynamics 8%
• Mixed-effects Model 8%
• Bacteroides 8%
• Late-onset 8%
• Peripheral Immune Activation 8%
• Lose Weight 8%
• Gene Count 8%
• Longitudinal Profile 8%
• Metagenomic Next-generation Sequencing (mNGS) 8%
• Disease Onset 8%
• Type III Secretion 8%
• Type IV Secretion 8%
• Metagenomic Data 8%
• Lipooligosaccharide 8%
• Microbial Community Changes 8%
• Taxonomic Structure 8%
• Sequence Effects 8%
• Healthy People 8%
• Pre-disease State 8%
• Severe Colitis 8%
• Glycosaminoglycan Degradation 8%
• KEGG Module 8%

Immunology and Microbiology

• Metagenome 100%
• Inflammatory Bowel Disease 100%
• Gut Microbiome 41%
• Metagenomics 33%
• Microorganism 25%
• Mouse Model 16%
• Taxon 16%
• Microbiome 16%
• Dynamics 8%
• T Cell 8%
• Normal Human 8%
• Bacteroides 8%
• Chemotaxis 8%
• T Cell Activation 8%
• Colitis 8%
• Type Three Secretion System 8%
• Type IV Secretion System 8%
• Cancer Growth Factor 8%