Development and mechanism of an enantioselective bromocycloetherification reaction via Lewis base/chiral Brønsted acid cooperative catalysis

Scott E. Denmark, Matthew T. Burk

Research output: Contribution to journalArticle

Abstract

The development of a binary catalyst system for bromocycloetherification, consisting of an achiral Lewis base and a chiral Brønsted acid, is described in detail. The results of preliminary kinetic studies are also presented. Chirality 26:343-354, 2013.

Original languageEnglish (US)
Pages (from-to)344-355
Number of pages12
JournalChirality
Volume26
Issue number7
DOIs
StatePublished - Jul 2014

Keywords

  • Lewis base
  • cooperative catalysis
  • enantioselective
  • halofunctionalization

ASJC Scopus subject areas

  • Analytical Chemistry
  • Catalysis
  • Pharmacology
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Development and mechanism of an enantioselective bromocycloetherification reaction via Lewis base/chiral Brønsted acid cooperative catalysis'. Together they form a unique fingerprint.

  • Cite this