TY - JOUR
T1 - Development and impedimetric evaluation of a magnetic interdigitated microelectrode
AU - Sanchez, Benjamin
AU - Vega, Didac
AU - Rodriguez, Angel
AU - Bragos, Ramon
AU - Marco, M. Pilar
AU - Valera, Enrique
N1 - Funding Information:
This work has been supported by the Spanish Ministry MICINN SAF2011-30067-C02-02 , by Redes de Investigacion del Instituto Carlos III (REDINSCOR, RD06/0003 ) and Fondo Europeo de Desarrollo Regional (FEDER). CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008–2011, Iniciativa Ingenio 2010 , Consolider Program , CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund. The Nb4D group (formerly Applied Molecular Receptors group, AMRg) is a consolidated Grup de Recerca de la Generalitat de Catalunya and has support from the Departament d’Universitats, Recerca i Societat de la Informacio la Generalitat de Catalunya (expedient 2009 SGR 1343).
Funding Information:
Dr. Enrique Valera received his Ph.D. degree in Electronic Technology from Universitat Politecnica de Catalunya (UPC), Spain, in 2008. He received his Bachelor's Degree in Electronic Engineering from Pontificia Universidad Catolica del Peru (PUCP), Peru, in 2003. In 2009, Dr. Valera joined the Applied Molecular Receptors group (AMRg, nowadays Nanobiotechnology for Diagnostics group, Nb4D) from the Spanish Council for Scientific Research (CSIC), Spain, as Post-Doc Researcher enjoying a Juan de la Cierva fellowship. In 2012, he joined to the Networking Research Center for Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Spain as Post-Doc Researcher. Since July 2014, Dr. Valera is Post-Doc Researcher at the Department of Chemistry at University of Illinois at Urbana-Champaign. Nowadays, his research interests are mainly focused on the development of immunosensors with application in the clinical diagnostics field. Dr. Valera has participated in several research projects (funded by EU and by the Spanish government), he is co-author of 14 publications of international relevance, and co-author of 2 patents.
PY - 2014/11
Y1 - 2014/11
N2 - A magnetic interdigitated microelectrode (m-IDμE) has been developed, characterized and evaluated. In order to demonstrate the potential use of these electrodes in the biosensors field, impedimetric measurements of bovine serum albumin (BSA) biofunctionalized magnetic μ-particles (BSAMP) were performed. Thanks to their magnetic capabilities and to the use of magnetic μ-particles, the developed electrodes were successfully regenerated and could be reused several times. The classical stepped-sine impedance spectroscopy (IS) technique and the state-of-art frequency response analyzer (FRA) multisine IS method based on the local polynomial method (LPM) were used as measurement techniques. The significant reduction of measuring time and accuracy of the multisine IS LPM-based technique reveals a promising performance for fast and accurate real-time on-line screening applications.
AB - A magnetic interdigitated microelectrode (m-IDμE) has been developed, characterized and evaluated. In order to demonstrate the potential use of these electrodes in the biosensors field, impedimetric measurements of bovine serum albumin (BSA) biofunctionalized magnetic μ-particles (BSAMP) were performed. Thanks to their magnetic capabilities and to the use of magnetic μ-particles, the developed electrodes were successfully regenerated and could be reused several times. The classical stepped-sine impedance spectroscopy (IS) technique and the state-of-art frequency response analyzer (FRA) multisine IS method based on the local polynomial method (LPM) were used as measurement techniques. The significant reduction of measuring time and accuracy of the multisine IS LPM-based technique reveals a promising performance for fast and accurate real-time on-line screening applications.
KW - Biofunctionalized magnetic μ-particles
KW - Biosensors
KW - Frequency response analyzer (FRA)
KW - Impedance spectroscopy (IS)
KW - Local polynomial method (LPM)
KW - Magnetic interdigitated microelectrode (m-IDμE)
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U2 - 10.1016/j.snb.2014.06.139
DO - 10.1016/j.snb.2014.06.139
M3 - Article
AN - SCOPUS:84904973378
SN - 0925-4005
VL - 203
SP - 444
EP - 451
JO - Sensors and Actuators, B: Chemical
JF - Sensors and Actuators, B: Chemical
ER -