Development and impedimetric evaluation of a magnetic interdigitated microelectrode

Benjamin Sanchez, Didac Vega, Angel Rodriguez, Ramon Bragos, M. Pilar Marco, Enrique Valera

Research output: Contribution to journalArticlepeer-review

Abstract

A magnetic interdigitated microelectrode (m-IDμE) has been developed, characterized and evaluated. In order to demonstrate the potential use of these electrodes in the biosensors field, impedimetric measurements of bovine serum albumin (BSA) biofunctionalized magnetic μ-particles (BSAMP) were performed. Thanks to their magnetic capabilities and to the use of magnetic μ-particles, the developed electrodes were successfully regenerated and could be reused several times. The classical stepped-sine impedance spectroscopy (IS) technique and the state-of-art frequency response analyzer (FRA) multisine IS method based on the local polynomial method (LPM) were used as measurement techniques. The significant reduction of measuring time and accuracy of the multisine IS LPM-based technique reveals a promising performance for fast and accurate real-time on-line screening applications.

Original languageEnglish (US)
Pages (from-to)444-451
Number of pages8
JournalSensors and Actuators, B: Chemical
Volume203
DOIs
StatePublished - Nov 2014
Externally publishedYes

Keywords

  • Biofunctionalized magnetic μ-particles
  • Biosensors
  • Frequency response analyzer (FRA)
  • Impedance spectroscopy (IS)
  • Local polynomial method (LPM)
  • Magnetic interdigitated microelectrode (m-IDμE)

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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