Abstract

We demonstrate a label-free biosensor imaging approach that utilizes a photonic-crystal surface to detect attachment of individual nanoparticles down to ~65x30x30nm3. Matching nanoparticle plasmon resonant-frequency to the photonic-crystal resonance substantially increases sensitivity of the approach.

Original languageEnglish (US)
Title of host publicationCLEO
Subtitle of host publicationScience and Innovations, CLEO_SI 2014
PublisherOptical Society of America (OSA)
ISBN (Print)9781557529992, 9781557529992
DOIs
StatePublished - 2014
EventCLEO: Science and Innovations, CLEO_SI 2014 - San Jose, CA, United States
Duration: Jun 8 2014Jun 13 2014

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Other

OtherCLEO: Science and Innovations, CLEO_SI 2014
CountryUnited States
CitySan Jose, CA
Period6/8/146/13/14

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Zhuo, Y., Hub, H., Chen, W., Lub, M., Tian, L., Yu, H., Long, K. D., Chow, E., King, W. P., Singamaneni, S., & Cunningham, B. T. (2014). Detection of single nanoparticles using photonic crystal enhanced microscopy. In CLEO: Science and Innovations, CLEO_SI 2014 (Optics InfoBase Conference Papers). Optical Society of America (OSA). https://doi.org/10.1364/cleo_si.2014.sm4p.6