Detection of single nanoparticles using photonic crystal enhanced microscopy

Yue Zhuo, Huan Hub, Weili Chen, Meng Lub, Limei Tian, Hojeong Yu, Kenneth D. Long, Edmond Chow, William P. King, Srikanth Singamaneni, Brian T. Cunningham

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We demonstrate a label-free biosensor imaging approach that utilizes a photonic-crystal surface to detect attachment of individual nanoparticles down to ~65x30x30nm3. Matching nanoparticle plasmon resonant-frequency to the photonic-crystal resonance substantially increases sensitivity of the approach.

Original languageEnglish (US)
Title of host publicationCLEO
Subtitle of host publicationScience and Innovations, CLEO_SI 2014
PublisherOptical Society of American (OSA)
ISBN (Print)9781557529992
StatePublished - 2014
EventCLEO: Science and Innovations, CLEO_SI 2014 - San Jose, CA, United States
Duration: Jun 8 2014Jun 13 2014

Other

OtherCLEO: Science and Innovations, CLEO_SI 2014
CountryUnited States
CitySan Jose, CA
Period6/8/146/13/14

Fingerprint

Photonic crystals
Microscopic examination
photonics
Nanoparticles
microscopy
nanoparticles
bioinstrumentation
crystal surfaces
Biosensors
crystals
attachment
resonant frequencies
Labels
Natural frequencies
Imaging techniques
sensitivity

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

Cite this

Zhuo, Y., Hub, H., Chen, W., Lub, M., Tian, L., Yu, H., ... Cunningham, B. T. (2014). Detection of single nanoparticles using photonic crystal enhanced microscopy. In CLEO: Science and Innovations, CLEO_SI 2014 Optical Society of American (OSA).

Detection of single nanoparticles using photonic crystal enhanced microscopy. / Zhuo, Yue; Hub, Huan; Chen, Weili; Lub, Meng; Tian, Limei; Yu, Hojeong; Long, Kenneth D.; Chow, Edmond; King, William P.; Singamaneni, Srikanth; Cunningham, Brian T.

CLEO: Science and Innovations, CLEO_SI 2014. Optical Society of American (OSA), 2014.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zhuo, Y, Hub, H, Chen, W, Lub, M, Tian, L, Yu, H, Long, KD, Chow, E, King, WP, Singamaneni, S & Cunningham, BT 2014, Detection of single nanoparticles using photonic crystal enhanced microscopy. in CLEO: Science and Innovations, CLEO_SI 2014. Optical Society of American (OSA), CLEO: Science and Innovations, CLEO_SI 2014, San Jose, CA, United States, 6/8/14.
Zhuo Y, Hub H, Chen W, Lub M, Tian L, Yu H et al. Detection of single nanoparticles using photonic crystal enhanced microscopy. In CLEO: Science and Innovations, CLEO_SI 2014. Optical Society of American (OSA). 2014
Zhuo, Yue ; Hub, Huan ; Chen, Weili ; Lub, Meng ; Tian, Limei ; Yu, Hojeong ; Long, Kenneth D. ; Chow, Edmond ; King, William P. ; Singamaneni, Srikanth ; Cunningham, Brian T. / Detection of single nanoparticles using photonic crystal enhanced microscopy. CLEO: Science and Innovations, CLEO_SI 2014. Optical Society of American (OSA), 2014.
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