@inproceedings{88b69f05c13d4862a7c156b959d46827,
title = "Detecting alterations in cell ultrastructure with optical imaging",
abstract = "Understanding cell functioning at the nanoscale has been hampered in part by the diffraction limited resolution of optical microscopy. We developed partial wave spectroscopic (PWS) microscopy that is capable of quantifying statistical properties of cell structure at the nanoscale. Our animal and human studies demonstrated that alterations in the nanoscale cell architecture is one of the earliest events in carcinogenesis and precedes any other known morphological changes at larger length scales (i.e. microarchitecture).",
author = "Vadim Backman and Hariharan Subramanian and Prabhakar Pradhan and Yang Liu and Ilker Capoglu and Rogers, \{Jeremy D.\} and Roy, \{Hemant K.\} and Allen Taflove",
year = "2009",
doi = "10.1109/IEMBS.2009.5333173",
language = "English (US)",
isbn = "9781424432967",
series = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009",
publisher = "IEEE Computer Society",
pages = "6325--6326",
booktitle = "Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society",
address = "United States",
note = "31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 ; Conference date: 02-09-2009 Through 06-09-2009",
}