Designing Artificial Metalloenzymes by Tuning of the Environment beyond the Primary Coordination Sphere

Keyphrases

• Coordination Sphere 100%
• Artificial Metalloenzymes 100%
• Metalloenzymes 50%
• Secondary Coordination Sphere 50%
• Heme 33%
• Native Enzymes 33%
• Metallocofactors 33%
• Metal Ions 16%
• Biological Function 16%
• Metal Center 16%
• Directed Evolution 16%
• Active Sites 16%
• Rational Design 16%
• Structural Features 16%
• Hydrogen Bonding Interaction 16%
• Computational Modeling 16%
• Protein Scaffold 16%
• Hydrophobic Bonding 16%
• Non-native 16%
• Catalytic Properties 16%
• Metal Catalysis 16%
• Natural Amino Acids 16%
• Metal Binding 16%
• Native Metals 16%
• Heteronuclear 16%
• Native Protein 16%
• Remaining Challenges 16%
• Non-heme 16%
• Biomimetic Catalyst 16%
• Coordination Environment 16%

Chemistry

• Metalloenzyme 100%
• Coordination Sphere 100%
• Heme 22%
• Hydrogen Bonding 11%
• Catalyst Property 11%
• Metal Ion 11%
• Amino Acid 11%