Designer antiandrogens join the race against drug resistance

Jatinder S. Josan; John A. Katzenellenbogen

doi:10.7554/eLife.00692

Designer antiandrogens join the race against drug resistance

Jatinder S. Josan
, John A. Katzenellenbogen

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

By using in silico models of the complexes formed by analogues of a cancer drug and its receptor, it may be possible to strategically redesign existing drugs and win the race against mutations that lead to drug resistance in prostate cancer. Copyright Josan and Katzenellenbogen.

Original language	English (US)
Article number	e00692
Journal	eLife
Volume	2013
Issue number	2
DOIs	https://doi.org/10.7554/eLife.00692
State	Published - Apr 9 2013

ASJC Scopus subject areas

General Neuroscience
General Immunology and Microbiology
General Biochemistry, Genetics and Molecular Biology

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10.7554/eLife.00692

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Designer antiandrogens join the race against drug resistance

Abstract

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