Design, Performance Evaluation, and Modeling of an Ultrahigh Resolution Detector Dedicated for Simultaneous SPECT/MRI

Xiaochun Lai, Liang Cai, Jia Wei Tan, Elena Maria Zannoni, Boris Odintsov, Ling Jian Meng

Research output: Contribution to journalArticlepeer-review

Abstract

In this article, we report design and preliminary performance evaluation of a CdTe detector module for use in an MR-compatible preclinical single-photon emission computed tomography system. The detector module consists of four CdTe detectors. Each of them has a CdTe crystal with a dimension of 1.125 cm \times 2.25 cm \times 2 mm (thickness). The crystal anode side is divided into 32 \times 64 square pixels with a width of 350 \mu \text{m} and attached to a custom-designed energy-resolved photon-counting (ERPC) application-specific integrated circuitry. The ERPC CdTe detector module has a median energy resolution of 7.0 keV across 8192 (4 \times 32 \times 64) pixels and 95% of the pixels have energy resolution better than 9 keV inside a Siemens clinical 3-T MR scanner; it has a median detection efficiency of 0.47 and 95% of the pixels have detection efficiency between 0.44 and 0.49; the detector spatial resolution enables one to observe the point response function (PRF) distortion caused by a 3T magnetic field. An analytical method has been developed to model this distortion and the corresponding modeled PRF has a root of mean-square error within 5%, compared to the experimental PRF.

Original languageEnglish (US)
Pages (from-to)42-50
Number of pages9
JournalIEEE Transactions on Radiation and Plasma Medical Sciences
Volume6
Issue number1
DOIs
StatePublished - Jan 1 2022
Externally publishedYes

Keywords

  • ASIC
  • CZT
  • CdTe
  • SPECT
  • SPECT/MRI
  • photon counting

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'Design, Performance Evaluation, and Modeling of an Ultrahigh Resolution Detector Dedicated for Simultaneous SPECT/MRI'. Together they form a unique fingerprint.

Cite this