Abstract
DNAzymes are DNA molecules with catalytic activities. Analyte-specific DNAzymes can be isolated with a combinatorial biology method called in vitro selection. For example, a Pb2+-specific DNAzyme cleaves its substrate DNA only in the presence of Pb2+. By attaching DNA-functionalized gold nanoparticles to DNAzymes, colorimetric sensors can be designed based on the different colors displayed by the different aggregate states of gold nanoparticles.
| Original language | English (US) |
|---|---|
| Title of host publication | 2nd Conference on Foundations of Nanoscience |
| Subtitle of host publication | Self-Assembled Architectures and Devices, FNANO 2005 |
| Pages | 226-227 |
| Number of pages | 2 |
| State | Published - 2005 |
| Event | 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005 - Snowbird, UT, United States Duration: Apr 24 2005 → Apr 28 2005 |
Other
| Other | 2nd Conference on Foundations of Nanoscience: Self-Assembled Architectures and Devices, FNANO 2005 |
|---|---|
| Country/Territory | United States |
| City | Snowbird, UT |
| Period | 4/24/05 → 4/28/05 |
ASJC Scopus subject areas
- Hardware and Architecture
- Electrical and Electronic Engineering