Abstract
This paper presents a design study of a single photon emission microscope (SPEM) system for small animal imaging using 1-125 labelled radiotracers. This system is based on the use of a very-high resolution gamma camera coupled to a converging non-multiplexing multiple pinhole collimator. This enables one to "zoom" into a small local region inside the object to extract imaging information with a very high spatial resolution and a reasonable sensitivity for gamma rays emitted from this local region. The SPEM system also includes a pinhole (or multiple pinhole) gamma camera that has a full angular coverage of the entire object. The designed imaging spatial resolution for the SPEM system is between 250 μm to 500 μm FWHM.
| Original language | English (US) |
|---|---|
| Article number | 1645012 |
| Pages (from-to) | 1168-1178 |
| Number of pages | 11 |
| Journal | IEEE Transactions on Nuclear Science |
| Volume | 53 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 2006 |
| Externally published | Yes |
Keywords
- Converging non-multiplexing multiple pinhole aperture
- Microscope
- Very-high spatial resolution gamma camera
ASJC Scopus subject areas
- Nuclear and High Energy Physics
- Nuclear Energy and Engineering
- Electrical and Electronic Engineering
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