Design and characterization of optofluidic photonic crystal structures for the detection of fluorescent-labeled biomolecules

J. M. Dawson, R. P. Tompkins, J. R. Nightingale, S. Yeldandi, K. Jo, X. A. Cao, L. A. Hornak, D. Korakakis, T. Myers, A. Timperman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The combination of optics and microfluidics into optofluidic systems has provided a means of creating portable integrated platforms for performing fluorescence emission analyses in fieldable systems. We present here the design of a photonic crystal transducer for highly sensitive and selective fluorescence-based biomolecule detection using a reduced-size lattice nanocavity tuned for resonance at emission wavelengths. This novel approach to biosensing is based upon photonic crystal defect structures that are engineered to act as waveguides, optical resonant cavities, and nanofluidic flow channels. This paper will discuss modeling, design, and nanofabrication of optofluidic photonic crystal (PhC) transducers in silicon and GaN materials. First-order results of PhC optical property characterization will be provided. Preliminary simulations indicate that fluorescence emission intensity inside of a PhC resonant defect nanocavity is enhanced to a level 26 times greater than emission outside of a defect due to resonant optical confinement and the Purcell effect.

Original languageEnglish (US)
Title of host publicationECS Transactions - Electrochemical Nano/Biosensors
Pages27-38
Number of pages12
Edition22
DOIs
StatePublished - 2008
Externally publishedYes
EventElectrochemical Nano/Biosensors - 213th Meeting of the Electrochemical Society - Phoenix, AZ, United States
Duration: May 18 2008May 23 2009

Publication series

NameECS Transactions
Number22
Volume13
ISSN (Print)1938-5862
ISSN (Electronic)1938-6737

Conference

ConferenceElectrochemical Nano/Biosensors - 213th Meeting of the Electrochemical Society
CountryUnited States
CityPhoenix, AZ
Period5/18/085/23/09

ASJC Scopus subject areas

  • Engineering(all)

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