Depletion of IQ motif-containing GTPase activating protein 2 (IQGAP2) reduces hepatic glycogen and impairs insulin signaling

Keyphrases

• Hepatic Glycogen 100%
• Insulin Signaling 100%
• GTPase-activating Protein 100%
• IQ Motif 100%
• Liver 40%
• Fed State 30%
• Metabolism 20%
• Knock-in Mouse Model 20%
• Glycogen Synthase Kinase 3 (GSK3) 20%
• Glycogen Synthesis 20%
• Phosphorylation 10%
• Co-immunoprecipitation (co-IP) 10%
• Knockdown 10%
• Scaffold Protein 10%
• Akt Phosphorylation 10%
• Fasted State 10%
• State Response 10%
• Hepatic Gene Expression 10%
• Glycogen 10%
• Insulin Signaling Pathway 10%
• Fatty Acid Uptake 10%
• Anabolic Effect 10%
• Metabolic Homeostasis 10%
• Glycogen Synthase 10%
• Catabolic Activity 10%
• Forkhead Box O3 (FOXO3) 10%
• Pericentral 10%

Biochemistry, Genetics and Molecular Biology

• Insulin Signaling 100%
• Glycogen Liver Level 100%
• GTPase-activating Protein 100%
• Metabolic Pathway 20%
• Knockout Mouse 20%
• Glycogenesis 20%
• Gene Expression 10%
• Homeostasis 10%
• Scaffold Protein 10%
• Immunoprecipitation 10%
• Mouse Model 10%
• Protein Kinase B 10%
• Glycogen Level 10%
• Fatty Acid Transport 10%
• Glycogen Synthase Kinase 3 10%
• Glycogen Synthase 10%
• Transcription Factor FKHRL1 10%