For parallelism to become tractable for mass programmers, shared-memory languages and environments must evolve to enforce disciplined practices that ban "wild shared-memory behaviors;" e.g., unstructured parallelism, arbitrary data races, and ubiquitous non-determinism. This software evolution is a rare opportunity for hardware designers to rethink hardware from the ground up to exploit opportunities exposed by such disciplined software models. Such a co-designed effort is more likely to achieve many-core scalability than a software-oblivious hardware evolution. This paper presents De-Novo, a hardware architecture motivated by these observations. We show how a disciplined parallel programming model greatly simplifies cache coherence and consistency, while enabling a more efficient communication and cache architecture. The DeNovo coherence protocol is simple because it eliminates transient states - verification using model checking shows 15X fewer reachable states than a state-of-theart implementation of the conventional MESI protocol. The De- Novo protocol is also more extensible. Adding two sophisticated optimizations, flexible communication granularity and direct cache-to-cache transfers, did not introduce additional protocol states (unlike MESI). Finally, DeNovo shows better cache hit rates and network traffic, translating to better performance and energy. Overall, a disciplined shared-memory programming model allows DeNovo to seamlessly integrate message passing-like interactions within a global address space for improved design complexity, performance, and efficiency.