Defining the energetic basis for a conformational switch mediating ligand-independent activation of mutant estrogen receptors in breast cancer

Christopher G Mayne, Weiyi Toy, Kathryn E Carlson, Trusha Bhatt, Sean W Fanning, Geoffrey L Greene, Benita S Katzenellenbogen, Sarat Chandarlapaty, John A Katzenellenbogen, Emad Tajkhorshid

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Biochemistry, Genetics and Molecular Biology