TY - JOUR
T1 - Deception through Mimicry
T2 - A Cellular Antiviral Strategy
AU - Wu, Nicholas C.
AU - Ward, Andrew B.
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/12/13
Y1 - 2018/12/13
N2 - Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein. Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein.
AB - Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein. Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein.
UR - http://www.scopus.com/inward/record.url?scp=85057859575&partnerID=8YFLogxK
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U2 - 10.1016/j.cell.2018.11.033
DO - 10.1016/j.cell.2018.11.033
M3 - Short survey
C2 - 30550784
AN - SCOPUS:85057859575
SN - 0092-8674
VL - 175
SP - 1728
EP - 1729
JO - Cell
JF - Cell
IS - 7
ER -