Decarboxylative ring-opening of 2-oxazolidinones: a facile and modular synthesis of β-chalcogen amines

Fábio Z. Galetto, Cleiton da Silva, Ricardo I.M. Beche, Renata A. Balaguez, Marcelo S. Franco, Francisco F. de Assis, Tiago E.A. Frizon, Xiao Su

Research output: Contribution to journalArticlepeer-review

Abstract

We report herein the synthesis of primary and secondary β-chalcogen amines through the regioselective ring-opening reaction of non-activated 2-oxazolidinones promoted by in situ generated chalcogenolate anions. The developed one-step protocol enabled the preparation of β-selenoamines, β-telluroamines and β-thioamines with appreciable structural diversity and in yields of up to 95%.

Original languageEnglish (US)
Pages (from-to)34496-34502
Number of pages7
JournalRSC Advances
Volume12
Issue number53
DOIs
StatePublished - Nov 30 2022

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering

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