Cytochrome P450s in the Era of Transcriptomics

Bernarda Calla, May R. Berenbaum

Research output: Chapter in Book/Report/Conference proceedingChapter


Cytochrome P450 (CYP) constitutes a large and hyperdiverse superfamily of enzymatic proteins that are present in organisms across all three kingdoms of life. By binding to iron as a cofactor, CYP enzymes catalyze oxidative reactions, including mono-oxygenation, hydroxylation, epoxidation and dealkylation, among others (Guengerich, 2001). The structural plasticity and diversity of CYP enzymes allow them to be used by living cells in numerous conserved developmental processes, as well as in non-conserved functions that include the production of secondary metabolites and the detoxification of xenobiotics.

Original languageEnglish (US)
Title of host publicationTranscriptomics in Entomological Research
PublisherCABI International
Number of pages14
ISBN (Electronic)9781789243147
ISBN (Print)9781789243130
StatePublished - Jan 1 2019

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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