Customization of load-bearing hydroxyapatite lattice scaffolds

Joseph Cesarano; Jennifer G. Dellinger; Michael P. Saavedra; David D. Gill; Russell D. Jamison; Benjamin A. Grosser; Janet M. Sinn-Hanlon; Michael S. Goldwasser

doi:10.1111/j.1744-7402.2005.02026.x

Customization of load-bearing hydroxyapatite lattice scaffolds

Joseph Cesarano, Jennifer G. Dellinger, Michael P. Saavedra, David D. Gill, Russell D. Jamison, Benjamin A. Grosser, Janet M. Sinn-Hanlon, Michael S. Goldwasser

Beckman Institute for Advanced Science and Technology

Research output: Contribution to journal › Article › peer-review

Abstract

Robocasting, a solid freeform fabrication technique, was used to develop lattices of hydroxyapatite (HA) that show promise as load-bearing scaffolds for bone repair. Additionally, the lattice scaffolds can be shaped into customized implants. A computed tomography (CT) scan of a damaged mandible was utilized to noninvasively design a lattice implant that could fill the damaged region. In a case study, the fit of the custom lattice scaffold was tested in a damaged mandible and "fit like a glove." Such implants may be able to replace numerous autograft procedures, thereby reducing surgical cost and complications associated with bone harvesting surgery.

Original language	English (US)
Pages (from-to)	212-220
Number of pages	9
Journal	International Journal of Applied Ceramic Technology
Volume	2
Issue number	3
DOIs	https://doi.org/10.1111/j.1744-7402.2005.02026.x
State	Published - 2005

ASJC Scopus subject areas

Ceramics and Composites
Condensed Matter Physics
Marketing
Materials Chemistry

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10.1111/j.1744-7402.2005.02026.x

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AU - Cesarano, Joseph

AU - Dellinger, Jennifer G.

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AU - Gill, David D.

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AU - Grosser, Benjamin A.

AU - Sinn-Hanlon, Janet M.

AU - Goldwasser, Michael S.

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AB - Robocasting, a solid freeform fabrication technique, was used to develop lattices of hydroxyapatite (HA) that show promise as load-bearing scaffolds for bone repair. Additionally, the lattice scaffolds can be shaped into customized implants. A computed tomography (CT) scan of a damaged mandible was utilized to noninvasively design a lattice implant that could fill the damaged region. In a case study, the fit of the custom lattice scaffold was tested in a damaged mandible and "fit like a glove." Such implants may be able to replace numerous autograft procedures, thereby reducing surgical cost and complications associated with bone harvesting surgery.

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Customization of load-bearing hydroxyapatite lattice scaffolds

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