Current trends and challenges in MRI acquisitions to investigate brain function

Bradley P. Sutton, Cheng Ouyang, Dimitrios C. Karampinos, Gregory A. Miller

Research output: Contribution to journalArticlepeer-review


Functional magnetic resonance imaging (fMRI) studies using the blood oxygenation level dependent (BOLD) response have become a widely used tool for noninvasive assessment of functional organization of the brain. Yet the technique is still fairly new, with many significant challenges remaining. Capitalizing on additional contrast mechanisms available with MRI, several other functional imaging techniques have been developed that potentially provide improved quantification or specificity of neuronal function. This article reviews the challenges and the current state of the art in MRI-based methods of imaging cognitive function.

Original languageEnglish (US)
Pages (from-to)33-42
Number of pages10
JournalInternational Journal of Psychophysiology
Issue number1
StatePublished - Jul 2009


  • BOLD
  • Cerebral blood flow
  • Cerebral blood volume
  • Cognitive neuroscience
  • Functional MRI
  • Neuroimaging

ASJC Scopus subject areas

  • General Neuroscience
  • Physiology (medical)
  • Neuropsychology and Physiological Psychology


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