TY - JOUR
T1 - Current alcohol use is associated with a reduced risk of hot flashes in midlife women
AU - Schiling, Chrissy
AU - Gallicchio, Lisa
AU - Miller, Susan R.
AU - Babus, Janice K.
AU - Lewis, Lynn M.
AU - Zacur, Howard
AU - Flaws, Jodi A.
N1 - Funding Information:
Acknowledgements — This study was supported by NIH grant AG18400 and a grant from the Women’s Health Research Group at the University of Maryland.
PY - 2005/11
Y1 - 2005/11
N2 - To examine the relation between current alcohol use, estradiol, estrone, and testosterone levels, and hot flashes in midlife women using a case-control study design. Methods: Cases were midlife women (45-54 years) who reported ever experiencing hot flashes. Controls were midlife women (45-54 years) who reported never experiencing hot flashes. Each participant completed a questionnaire and provided a blood sample that was used to measure estradiol, estrone, and testosterone levels by enzyme-linked immunosorbent assay. Results: The results indicate that current alcohol use (at least one day per month) was significantly associated with a reduced risk of hot flashes compared to non-use of alcohol, independent of age and smoking habits. The hot flashes experienced by current alcohol users were less severe and less frequent than those experienced by non-users of alcohol. Further, current alcohol users had similar levels of estradiol, estrone, and testosterone compared to non-users of alcohol. Conclusions: These data suggest that current alcohol use is associated with a reduced risk of any, severe, and frequent hot flashes in midlife women by a mechanism that may not include changes in sex steroid hormone levels.
AB - To examine the relation between current alcohol use, estradiol, estrone, and testosterone levels, and hot flashes in midlife women using a case-control study design. Methods: Cases were midlife women (45-54 years) who reported ever experiencing hot flashes. Controls were midlife women (45-54 years) who reported never experiencing hot flashes. Each participant completed a questionnaire and provided a blood sample that was used to measure estradiol, estrone, and testosterone levels by enzyme-linked immunosorbent assay. Results: The results indicate that current alcohol use (at least one day per month) was significantly associated with a reduced risk of hot flashes compared to non-use of alcohol, independent of age and smoking habits. The hot flashes experienced by current alcohol users were less severe and less frequent than those experienced by non-users of alcohol. Further, current alcohol users had similar levels of estradiol, estrone, and testosterone compared to non-users of alcohol. Conclusions: These data suggest that current alcohol use is associated with a reduced risk of any, severe, and frequent hot flashes in midlife women by a mechanism that may not include changes in sex steroid hormone levels.
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U2 - 10.1093/alcalc/agh191
DO - 10.1093/alcalc/agh191
M3 - Article
C2 - 16087658
AN - SCOPUS:27744475480
SN - 0735-0414
VL - 40
SP - 563
EP - 568
JO - Alcohol and Alcoholism
JF - Alcohol and Alcoholism
IS - 6
ER -