Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

Ying Li; Yugang Bai; Nan Zheng; Yang Liu; Gretchen A. Vincil; Benjamin J. Pedretti; Jianjun Cheng; Steven C. Zimmerman

doi:10.1039/c5cc09430e

Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

Ying Li, Yugang Bai, Nan Zheng, Yang Liu, Gretchen A. Vincil, Benjamin J. Pedretti, Jianjun Cheng, Steven C. Zimmerman

Research output: Contribution to journal › Article › peer-review

Abstract

Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.

Original language	English (US)
Pages (from-to)	3781-3784
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	19
DOIs	https://doi.org/10.1039/c5cc09430e
State	Published - 2016

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/c5cc09430e

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title = "Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores",

abstract = "Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.",

author = "Ying Li and Yugang Bai and Nan Zheng and Yang Liu and Vincil, {Gretchen A.} and Pedretti, {Benjamin J.} and Jianjun Cheng and Zimmerman, {Steven C.}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",

year = "2016",

doi = "10.1039/c5cc09430e",

language = "English (US)",

volume = "52",

pages = "3781--3784",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

AU - Li, Ying

AU - Bai, Yugang

AU - Zheng, Nan

AU - Liu, Yang

AU - Vincil, Gretchen A.

AU - Pedretti, Benjamin J.

AU - Cheng, Jianjun

AU - Zimmerman, Steven C.

PY - 2016

Y1 - 2016

N2 - Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.

AB - Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.

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U2 - 10.1039/c5cc09430e

DO - 10.1039/c5cc09430e

M3 - Article

AN - SCOPUS:84961226751

SN - 1359-7345

VL - 52

SP - 3781

EP - 3784

JO - Chemical Communications

JF - Chemical Communications

IS - 19

ER -

Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

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