Cross-imaging system comparison of backscatter coefficient estimates from a tissue-mimicking material

Kibo Nam, Ivan M. Rosado-Mendez, Lauren A. Wirtzfeld, Viksit Kumar, Ernest L. Madsen, Goutam Ghoshal, Alexander D. Pawlicki, Michael L. Oelze, Roberto J. Lavarello, Timothy A. Bigelow, James A. Zagzebski, William D. O'Brien, Timothy J. Hall

Research output: Contribution to journalArticlepeer-review


A key step toward implementing quantitative ultrasound techniques in a clinical setting is demonstrating that parameters such as the ultrasonic backscatter coefficient (BSC) can be accurately estimated independent of the clinical imaging system used. In previous studies, agreement in BSC estimates for well characterized phantoms was demonstrated across different laboratory systems. The goal of this study was to compare the BSC estimates of a tissue mimicking sample measured using four clinical scanners, each providing RF echo data in the 1-15 MHz frequency range. The sample was previously described and characterized with single-element transducer systems. Using a reference phantom for analysis, excellent quantitative agreement was observed across the four array-based imaging systems for BSC estimates. Additionally, the estimates from data acquired with the clinical systems agreed with theoretical predictions and with estimates from laboratory measurements using single-element transducers.

Original languageEnglish (US)
Pages (from-to)1319-1324
Number of pages6
JournalJournal of the Acoustical Society of America
Issue number3
StatePublished - Sep 2012

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Acoustics and Ultrasonics


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