Critical appraisal of Perez et al: Jugular venous oxygen saturation or arteriovenous difference of lactate content and outcome in children with severe traumatic brain injury

Jeffrey Alten, M. Michele Mariscalco

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Objective: To review the findings and discuss the implications of jugular venous bulb oxygenation monitoring in children with severe traumatic brain injury. Design: A critical appraisal of Perez et al, Jugular venous oxygen saturation or arteriovenous difference of lactate content and outcome in children with severe traumatic brain injury. Pediatr Crit Care Med 2003; 4:33-58. Findings: Two episodes of jugular venous bulb desaturation and abnormal values of arteriovenous difference in lactate content are associated with poor neurologic outcome in children with severe traumatic brain injury-risk ratio 6.6 (95% confidence interval, 1.5-29.7) and risk ratio 17.6 (95% confidence interval, 2.5-122.5), respectively. This confirms the findings of previously reported adult studies. Conclusions: This study is the first to demonstrate that jugular venous monitoring may aid in predicting the neurologic outcome of children with severe traumatic brain injury. More studies need to be performed (particularly on safety) before adopting jugular venous bulb oxygenation monitoring as a prediction tool or, ultimately, as a therapeutic intervention to help manage and improve outcome for children with severe traumatic brain injury.

    Original languageEnglish (US)
    Pages (from-to)480-482
    Number of pages3
    JournalPediatric Critical Care Medicine
    Volume6
    Issue number4
    DOIs
    StatePublished - Jul 2005

    Keywords

    • Children
    • Jugular venous saturation
    • Traumatic brain injury

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Critical Care and Intensive Care Medicine

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