Keyphrases
Mouse Model
100%
Genome Editing
100%
Huntington's Disease
100%
Cas9 Protein
100%
Motor Deficits
100%
Huntingtin
75%
Cas9 nuclease
50%
Striatum
50%
Neurodegenerative Diseases
50%
Trinucleotide Expansion
50%
Mutant Huntingtin
50%
In Vivo Genome Editing
25%
Mutated Genes
25%
Mutant Protein
25%
Single Guide RNA (sgRNA)
25%
RNA-based
25%
CRISPR-Cas9 System
25%
Gene Function
25%
In Vivo Delivery
25%
DNA Double-strand Breaks
25%
Adjacent Structures
25%
Frameshift
25%
Adeno-associated Viral Vector
25%
Staphylococcus Aureus
25%
Exon 1
25%
Autosomal Dominant
25%
CAG Trinucleotide Repeat
25%
Cas9 Ortholog
25%
CRISPR-Cas9 Technology
25%
Neuronal Inclusions
25%
Biochemistry, Genetics and Molecular Biology
Lifespan
100%
Genome Editing
100%
CRISPR/Cas9
100%
Mouse Model
100%
Cas9
75%
Huntingtin
75%
Trinucleotide Repeat Expansion
50%
RNA
25%
Exon
25%
Orthology
25%
Guide RNA
25%
Mutant Protein
25%
Gene Function
25%
Adeno Associated Virus Vector
25%
Staphylococcus Aureus
25%
Autosomal Dominant Inheritance
25%
Endonuclease
25%
Nuclease
25%
Double-Strand DNA Break
25%
Medicine and Dentistry
Lifespan
100%
Genome Editing
100%
Clustered Regularly Interspaced Short Palindromic Repeat
100%
Cas9
100%
Huntington's Disease
100%
Huntingtin
42%
Striatum
28%
Neurodegenerative Disorder
28%
Trinucleotide Repeat
28%
Nuclease
14%
Guide RNA
14%
Exon
14%
Gene Function
14%
Staphylococcus Aureus
14%
Adeno Associated Virus Vector
14%
Mutant Protein
14%
Autosomal Dominant Inheritance
14%
Orthology
14%
Endonuclease
14%
Double-Strand DNA Break
14%
Neuroscience
Huntington's Disease
100%
CRISPR
100%
Huntingtin
75%
In Vivo
50%
Striatum
50%
Neurodegenerative Disorder
50%
Trinucleotide Repeat
50%
Exon
25%
Mutant Protein
25%
Guide RNA
25%
Double Stranded DNA
25%
Gene Function
25%
Endonuclease
25%
Nuclease
25%
Adeno Associated Virus Vector
25%