CRISPR-Cas Gatekeeper: Slow on the Uptake but Gets the Job Done

Research output: Contribution to journalShort survey


Microbial CRISPR-Cas acts as a defense, but also as a gatekeeper controlling the flow of new genes into microbial genomes. In a recent Cell paper, Jiang et al. (2016) uncover the functional importance of transcription-dependent RNA targeting in type III-A CRISPR-Cas antiviral defense and provide insight into the co-evolution of virus-host symbioses.

Original languageEnglish (US)
Pages (from-to)135-137
Number of pages3
JournalCell Host and Microbe
Issue number2
StatePublished - Jan 1 2016


ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

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