Correlation of multi-scale modeling and experimental results for the elastic moduli of cortical and trabecular bone

Ekaterina Novitskaya, Elham Hamed, Jun Li, Iwona Jasiuk, Joanna McKittrick

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cortical and trabecular bones were modeled as nanocomposite materials with hierarchical structures spanning from collagen-mineral level to cortical and trabecular bone levels. In order to verify theoretical models, compression testing was done on cortical and trabecular bovine femur bone samples and the experimental data were compared with the theoretical results. The micro-computed tomography technique was used to characterize the porosities and structures of these bones at different length scales and to provide the inputs needed for the modeling. To obtain more insight on the structure of bone, especially on the interaction of the main constituents (collagen and mineral phases), both cortical and trabecular bone samples were deproteinized and demineralized and, afterwards, tested in compression. This information was used to fine-tune our multi-scale model representing bone as an interpenetrating composite material. Very good agreement was found between the theory and experiments for the elastic moduli of untreated, deproteinized, and demineralized cortical and trabecular bones.

Original languageEnglish (US)
Title of host publicationMechanics of Biological Systems and Materials - Proceedings of the 2012 Annual Conference on Experimental and Applied Mechanics
Pages99-107
Number of pages9
DOIs
StatePublished - Jan 1 2013
Event2012 Annual Conference on Experimental and Applied Mechanics - Costa Mesa, CA, United States
Duration: Jun 11 2012Jun 14 2012

Publication series

NameConference Proceedings of the Society for Experimental Mechanics Series
Volume5
ISSN (Print)2191-5644
ISSN (Electronic)2191-5652

Other

Other2012 Annual Conference on Experimental and Applied Mechanics
CountryUnited States
CityCosta Mesa, CA
Period6/11/126/14/12

Fingerprint

Bone
Elastic moduli
Collagen
Minerals
Compression testing
Tomography
Nanocomposites
Porosity
Composite materials
Experiments

Keywords

  • Cortical bone
  • Demineralization
  • Deproteinization
  • Elastic moduli
  • Multi-scale modeling
  • Trabecular bone

ASJC Scopus subject areas

  • Engineering(all)
  • Computational Mechanics
  • Mechanical Engineering

Cite this

Novitskaya, E., Hamed, E., Li, J., Jasiuk, I., & McKittrick, J. (2013). Correlation of multi-scale modeling and experimental results for the elastic moduli of cortical and trabecular bone. In Mechanics of Biological Systems and Materials - Proceedings of the 2012 Annual Conference on Experimental and Applied Mechanics (pp. 99-107). (Conference Proceedings of the Society for Experimental Mechanics Series; Vol. 5). https://doi.org/10.1007/978-1-4614-4427-5_15

Correlation of multi-scale modeling and experimental results for the elastic moduli of cortical and trabecular bone. / Novitskaya, Ekaterina; Hamed, Elham; Li, Jun; Jasiuk, Iwona; McKittrick, Joanna.

Mechanics of Biological Systems and Materials - Proceedings of the 2012 Annual Conference on Experimental and Applied Mechanics. 2013. p. 99-107 (Conference Proceedings of the Society for Experimental Mechanics Series; Vol. 5).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Novitskaya, E, Hamed, E, Li, J, Jasiuk, I & McKittrick, J 2013, Correlation of multi-scale modeling and experimental results for the elastic moduli of cortical and trabecular bone. in Mechanics of Biological Systems and Materials - Proceedings of the 2012 Annual Conference on Experimental and Applied Mechanics. Conference Proceedings of the Society for Experimental Mechanics Series, vol. 5, pp. 99-107, 2012 Annual Conference on Experimental and Applied Mechanics, Costa Mesa, CA, United States, 6/11/12. https://doi.org/10.1007/978-1-4614-4427-5_15
Novitskaya E, Hamed E, Li J, Jasiuk I, McKittrick J. Correlation of multi-scale modeling and experimental results for the elastic moduli of cortical and trabecular bone. In Mechanics of Biological Systems and Materials - Proceedings of the 2012 Annual Conference on Experimental and Applied Mechanics. 2013. p. 99-107. (Conference Proceedings of the Society for Experimental Mechanics Series). https://doi.org/10.1007/978-1-4614-4427-5_15
Novitskaya, Ekaterina ; Hamed, Elham ; Li, Jun ; Jasiuk, Iwona ; McKittrick, Joanna. / Correlation of multi-scale modeling and experimental results for the elastic moduli of cortical and trabecular bone. Mechanics of Biological Systems and Materials - Proceedings of the 2012 Annual Conference on Experimental and Applied Mechanics. 2013. pp. 99-107 (Conference Proceedings of the Society for Experimental Mechanics Series).
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