Coordination chemistry of 3-mercapto-2-(mercaptomethyl)propanoic acid (dihydroasparagusic acid) with iron and nickel

Phillip I. Volkers, Thomas Rauchfuss, Scott R. Wilson

Research output: Contribution to journalArticlepeer-review

Abstract

The first transition-metal complexes bearing the natural product dihydroasparagusic acid, (HSCH2)2CHCO2H, as a ligand are reported. Various coordination modes and nuclearities are demonstrated for the chelating ligand by a series of iron and nickel complexes. Fe2[(SCH2)2CHCO2H](CO)6 retains carbonyl substitution reactivity typical of Fe2(SR) 2(CO)6 complexes, yet carboxy coordination to Fe I was unobserved. Coupling of the carboxylic acid with amines yields the corresponding amides Fe2[(SCH2)2CHC(O)NHR] (CO)6 (R = Et, gly-O-tBu). Fe2[(SCH2) 2CHCO2H](CO)4(PMe3)2 catalyzes H2 production, but no better than unfunctionalized alkyl dithiolate analogs. Reactions of the ligand with NiCl2(dppe) afforded mono-, di-, and trinuclear complexes. Noteworthy is Ni3[(SCH 2)2CHCO2]2(dppe)2, which features an octahedrally coordinated NiII center linked to a pair of square-planar NiII centers.

Original languageEnglish (US)
Pages (from-to)4793-4799
Number of pages7
JournalEuropean Journal of Inorganic Chemistry
Issue number23
DOIs
StatePublished - Dec 4 2006

Keywords

  • Bridging ligands
  • Coordination modes
  • Iron
  • Nickel
  • S ligands

ASJC Scopus subject areas

  • Inorganic Chemistry

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